Saturday, March 3, 2012

Research from Royal Adelaide Hospital yields new data on atrial septal defects.(Report)

According to a study from Adelaide, Australia, "Information regarding Left atrial (LA) substrate in conditions predisposing to atrial fibrillation (AF) is limited. This study sought to characterize the Left atrial remodeling that results from chronic atrial stretch caused by atrial septal defect (ASD)."

"Eleven patients with hemodynamically significant ASDs and 12 control subjects were studied. The following were evaluated using multipolar catheters: effective refractory period (ERP) at 7 sites, P-wave duration (PWD), conduction time, and inducibility of AF. LA electroanatomic maps were created to determine atrial activation, and regional conduction and voltage abnormalities. …

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